ÚHKT - Ústav hematologie a krevní transfuze
Úsek pro vědu a výzkum

NRL for immunohematology

The workplace is integrated into the Complement of laboratories IHBT. It continuously maintains independent and unbiased assessment of professional competence of the Complement of laboratories according to the standard ČSN EN ISO 15189, whose application is verified by the Czech Institute for Accreditation. Examination methods within the scope of accreditation are defined by the attachment of the Accreditation Certificate in the current version, which is available on the website IHBT.

NRL performs specialized immunohematological examinations aimed at solving difficult cases in blood group determination, pre-transfusion examinations and antibody examinations from all laboratories in the Czech and Slovak republics; it also solves difficult cases of immunohematological complications in pregnancy, autoimmune hemolytic conditions and interference of biological treatment with monoclonal antibodies with laboratory tests. Immunohematological diagnostics is gradually being expanded with molecular-biological methods, including blood group genotyping using microarrays (BloodChip and FluoGene). 

The laboratory maintains a bank of frozen rare erythrocytes and antibodies (as a member of the international exchange group SCARF). The laboratory also coordinates the national register of rare blood donors and cooperates with the bank of rare frozen blood at UVN and contributes to the International Register of Rare Donors in Bristol in Great Britain, to which it has access and at the same time has the opportunity to coordinate the acquisition of an appropriate transfusion product. It cooperates with the International Blood Group Reference Laboratory in Bristol and a number of other world immunohematological workplaces in verifying unusual findings.

The laboratory verifies newly introduced reagents and systems for determining blood markers and antibodies within the Czech Republic.

The laboratory prepares samples for external quality control of immunohematological examinations in the Czech Republic within SEKK s.r.o. - cycles Immunohematology (IH) and Direct Antiglobulin Test (PAT). 
Furthermore, platelet, granulocyte and HLA antibodies are examined in the laboratory and subsequently platelet antigens are typed. The laboratory also examines cases of heparin-induced thrombocytopenia (HIT).

Employees are bound by confidentiality under the Law on health services, 372/2011 Coll.

Trust and high data security is one of the fundamental priorities within the activities of the Complement of laboratories IHBT. The implemented procedures are carried out in accordance with the Law on the Processing of Personal Data 110/2019 Coll., and Regulation of the European Parliament and Council of the EU 2016/679, of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data and repealing Directive 95/46/ES. More information is available on the website IHBT.