Laboratory for Hemostasis Disorders

The workplace is incorporated into the Complement of laboratories IHBT. It continuously defends an independent and impartial assessment of the professional competence of the Complement of laboratories according to the standard ČSN EN ISO 15189, the application of which is verified by the Czech Institute for Accreditation. The examination methods within the scope of accreditation are defined by the annex of the Accreditation Certificate in the current version, which is available on the website IHBT.

The Laboratory for Hemostasis Disorders (LPH) is engaged in the diagnosis and pathophysiology of hemostasis disorders. It was established as a research coagulation laboratory in the 1970s and developed in parallel with the advancement of scientific discoveries in the field of coagulation and hemostasis. Today, its activities combine routine and consultative work in laboratory diagnostics and scientific research work supported by grants. The laboratory closely collaborates with the outpatient Centre for Thrombosis and Hemostasis and  NRL for Hemostasis Disorders.

The laboratory is focused on comprehensive hemostasis diagnostics, both routine and specialized, including translational medicine aimed at hemostasis disorders and molecular genetic screening of congenital hemostasis disorders. It specializes in comprehensive phenotypic and genetic screening of patients with congenital bleeding disorders (hemophilia, von Willebrand disease, rare congenital disorders of other coagulation factors and congenital thrombocytopathies) and with congenital thrombotic disorders (antithrombin deficiency, protein S deficiency, protein C deficiency). An integral part of the laboratory's activities is differential diagnosis of thrombotic microangiopathy (TMA) and complete diagnosis of thrombotic thrombocytopenic purpura (TTP). The laboratory also focuses on monitoring anticoagulant and antiplatelet therapy and monitoring predictive factors for disease relapse. It also performs molecular-genetic examinations to determine hemophilia carrier status and for prenatal examination of hemophilia and other hemostasis disorders. When introducing innovative hemostasis examination methods, the laboratory collaborates with cardiological, nephrological, pediatric, neurological, obstetric, genetic and other departments. It performs consultative work in laboratory diagnostics of hemostasis disorders for the entire Czech Republic. Laboratory staff regularly publish and contribute to publications in peer-reviewed journals. The workplace participates in practical and theoretical training of secondary and university employees preparing for specialist examinations in hematology and other laboratory disciplines. The laboratory also participates in the training of postgraduate students to obtain a Ph.D. degree.

The quality of its activities is monitored through participation in external quality control (EQC) of international organizations such as UK NEQAS and ECAT. 

Employees are bound by confidentiality according to the Act on Health Services, 372/2011 Coll.

Trust and high data security is one of the basic priorities in the activities of the Complement of laboratories IHBT. The implemented procedures are carried out in accordance with the Personal Data Processing Act 110/2019 Coll., and Regulation of the European Parliament and Council of the EU 2016/679 of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data and repealing Directive 95/46/EC. More information is available on the website IHBT.

Part of the laboratory is NRL for Hemostasis Disorders

• List of department employees
• Publication activity

External quality control certificates: ECAT, NEQAS coagulation, NEQAS MolGenHCert, NEQAS Thrombophilia, NEQAS MolGenH40.