Academic clinical evaluations
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UHKT-CAML-NK-01 "Adoptive transfer of haploidentical ex vivo expanded NK cells to patients with refractory or relapsed acute myeloid leukemia within allogeneic hematopoietic stem cell transplantation from a haploidentical related donor after a sequential conditioning protocol. Monocentric, open-label phase IIa dose escalation study." |
Completed |
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UHKT-VSL-CCS-01 "Efficacy of manufacturing, clinical safety and efficacy of virus-specific T lymphocytes isolated on the CliniMACS Prodigy® device using the Cytokine Capture system for patients after allogeneic transplantation." |
Completed |
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TCB-202-001 "Clinical evaluation of safety and efficacy of allogeneic γδ T lymphocytes expanded ex vivo (OmnImmune®) in patients with relapsed or resistant acute myeloid leukemia (AML) who cannot or are unwilling to undergo high-dose salvage chemotherapy and/or allogeneic hematopoietic stem cell transplantation. Open-label phase I dose escalation study." |
Completed |
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UHKT-CAR19-01 "Clinical evaluation of safety and efficacy of autologous CART19 lymphocytes in patients with relapsed or refractory acute B-lymphoblastic leukemia (B-ALL) or with relapsed or refractory B-cell non-Hodgkin lymphoma (B-NHL). Open-label phase I dose escalation study." |
Open |
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UHKT-CAR123-01 "Safety and efficacy of autologous T lymphocytes with chimeric antigen receptor anti-CD123 in patients with relapsed or refractory CD123 positive hematological malignancy. Open-label phase I dose escalation study." |
Open |