ÚHKT - Ústav hematologie a krevní transfuze
Úsek pro vědu a výzkum

Support for innovative environment

The Institute of Hematology and Blood Transfusion has established, in cooperation with the Technology Agency of the Czech Republic (TAČR), an internal innovation environment that enables it to implement a complete development cycle for medicinal products of modern and gene therapy.

The innovation cycle is based on the requirements of clinical physicians who, in caring for IHBT patients, encounter interesting clinical problems and formulate assignments to inspire basic research at IHBT.
IHBT has built infrastructure for applied research that enables successful basic research projects to be implemented in practice – for example, to prepare the production of a new medicinal product or validate a new diagnostic method.
The results of applied research must be verified in patients through clinical evaluation. The outputs of clinical evaluation are then passed back to clinical physicians and can inspire further research development.

TAČR Innovation Projects

In cooperation with the Technology Agency of the Czech Republic, IHBT implements applied research projects of the "proof-of-concept" type, which have invaluable significance for the phase of technology transfer of basic research outputs into therapeutic practice.

Currently, a project from the 4th public call of TAČR SIGMA number TQ11000057 – "Successful Commercialization of Hematological, Hematologic-Oncological and Immunotherapeutic Products II" is being implemented. Within this project, which was initiated in 2024, the following subprojects are being gradually implemented:

CTT030

Introduction of phenotypic tests of modern therapy medicinal products under Good Manufacturing Practice

CTT031

Transfection vectors for clinical research of BCMA/CD19 CAR-T lymphocytes in pharmaceutical quality and their accessories

CTT032

New molecular genetic diagnostic method for detection of partial tandem duplication in the KMT2A gene in patients with myelodysplastic neoplasms