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Science and research

Laboratory of Molecular Epidemiology of Viruses

The main aim of the laboratory is to contribute to the elucidation of the role of viruses in the development of human diseases, mainly cancer. Viral infections are detected using molecular-biological methods and assessment of viral-specific antibodies presence. The research is focused on the causal link of human papillomaviruses and malignant diseases of anogenital tract and a part of head and neck cancer cases, as well as the follow-up of markers of broad spectrum of human polyomaviruses in various diagnoses.

For the detection of the serological response we prepare antigens derived from proteins of individual viruses using recombinant technologies. Virus-specific antibodies elicited during natural infection are detected by means of virus-like particles based on capsid proteins. Other recombinant antigens are prepared as glutathione-S-transferase bound papillomavirus oncoproteins.

In cooperation with the Prague Voice Centre the laboratory is responsible for a 5-year clinical study IIIb to ascertain the effect of quadrivalent HPV vaccine in patients suffering from the recurrent laryngeal papillomatosis, caused exclusively by HPV 6 and HPV11 antibodies included in the vaccine. Vaccination might extend the intervals between individual recurrences or prevent them.


Quick contact

Head of Science and Research Division
Tel:+420 221 977 208

Deputy head of Science and Research Division
Tel:+420 221 977 269
Tel:+420 221 977 364

Secretary
Tel:+420 221 977 247


Opening hours

Ambulance
Mo – Fr: 7:00–18:00
Weekends: 9:00–13:00

Donors
Mo – Fr: 7:00–10:30

Visitors
Inpatient department
Mo – Fr: 13:00–18:00

ICU and Transplant unit
Mo – Fr: 14:00–17:00

How to find us

map

Ústav hematologie a krevní transfuze
(​Institute of Hematology and Blood Transfusion)

U Nemocnice 2094/1
128 20 Praha 2

The nearest underground station: Karlovo náměstí (line B)

The nearest tram station: Karlovo náměstí (10, 16, 22), Moráň (3, 6, 10, 16, 18, 24)

The nearest bus station: U nemocnice (291), Karlovo náměstí (176)

How to get here