Science and research

International Projects

1. EUTOS for CML (European Treatment and Outcome Study for CML, European LeukemiaNet - ELN)

  • Our laboratory is the EUTOS laboratory and reference laboratory for the Czech Republic.
  • We provide the validation of conversion factor to harmonize the quantification of BCR-ABL1 transcript in the Czech and Slovak Republics when reporting results on the International Scale.


2. EUTOS-MR (EUTOS for CML III, Path to cure CML; ELN)

  • Our laboratory is an EUTOS MR4.5 laboratory; we provide the standardized measurement of major molecular response.
  • We participate in defining and standardizing the monitoring of deep molecular response (MR4.0, MR4.5, MR5.0).


3. CAMN107AIC05 - A prospective, randomized, open label two arm Phase III study to evaluate treatment free remission (TFR) rate in patients with Philadelphia-positive CML after two different durations of consolidation treatment with nilotinib (Novartis)

  • We perform molecular monitoring of the BCR-ABL1 transcript level on the International Scale and BCR-ABL1 kinase domain mutation analyses of patients from three EU countries.
  • Within this study we participate in defining of the deep molecular response.


4. EURO-SKI; EUROpean Stop TKI 

  • As an EUTOS MR4.5 laboratory, we perform the monitoring of the deep molecular response in all patients involved in the study from the Czech Republic.


5. EUREKA; European survey on the assessment of deep molecular response in chronic phase CML patients after at least two years of therapy with tyrosine kinase inhibitors (EUTOS for CML, ELN)

  • Our laboratory is the principal investigator of the project for the Czech Republic.
  • We perform the monitoring of the deep molecular response in patients involved in this study from three hematology centres in the Czech Republic.

Quick contact

Head of Science and Research Division
Tel:+420 221 977 305

Deputy head of Science and Research Division
Tel:+420 221 977 648

Tel:+420 221 977 144

Opening hours

Mo – Fr: 7:00–18:00
Weekends: 9:00–13:00

Mo – Fr: 7:00–10:30

Inpatient department
Mo – Fr: 13:00–18:00

ICU and Transplant unit
Mo – Fr: 14:00–17:00

How to find us


Ústav hematologie a krevní transfuze
(​Institute of Hematology and Blood Transfusion)

U Nemocnice 2094/1
128 00 Praha 2

The nearest underground station: Karlovo náměstí (line B)

The nearest tram station: Karlovo náměstí (10, 16, 22), Moráň (3, 6, 10, 16, 18, 24)

The nearest bus station: U Nemocnice (148), Karlovo náměstí (176)

How to get here